development and cytoxicity evaluation of nanomicelle carriers for delivery of all-trans retinoic acid

Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation

A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...

Gelatin Microspheres for the Controlled Release of All-trans-Retinoic Acid Topical Formulation and Drug Delivery Evaluation

A topical o/w cream containing tretinoin microspheres was prepared. Gelatin microspheres of tretinoin were prepared using coacervation method. These microspheres contained about 50% w/w tretinoin. The particle size range of microspheres was between 90-150 m m. In vitro drug release from microspheres and a cream formulation was studied. It was shown that drug release from microspheres followed H...

gelatin microspheres for the controlled release of all-trans-retinoic acid topical formulation and drug delivery evaluation

a topical o/w cream containing tretinoin microspheres was prepared. gelatin microspheres of tretinoin were prepared using coacervation method. these microspheres contained about 50% w/w tretinoin. the particle size range of microspheres was between 90-150 m m. in vitro drug release from microspheres and a cream formulation was studied. it was shown that drug release from microspheres followed h...

All-trans-retinoic acid: measurement

A quantitative determination of physiological levels of all-trans-retinoic acid (vitamin A acid) in human serum has been developed. A double-phase extraction of 3.5 ml of serum followed by a specific and sensitive high performance liquid chromatography procedure allowed measurement of levels down to 1 ng/ml. Serum concentrations in 37 fasting volunteers ranged from 2.7 to 4.2 ng/ml and fitted a...

Development and evaluation of bio-nanoparticles as novel drug carriers for the delivery of Donepezil

The purpose of the present study was to formulate and evaluate donepezil loaded bio-nanoparticles for effective treatment of Alzheimer’s disease. For the preparation of bio-nanoparticles biomaterial was isolated from fruits of Carica papaya by an economic method. The biomaterial recovered from the concentrate was subjected for various physicochemical properties like color, solubility, ...

nanomicelle carriers for delivery of alfa-tocopherol: formulation and characterization